Nitazoxanide works by inhibiting the growth and spread of certain parasites and bacteria in the body. It interferes with the energy production of these microorganisms by blocking an enzyme called pyruvate ferredoxin oxidoreductase (PFOR), which is crucial for their survival and replication. By disrupting this enzyme's function, nitazoxanide effectively halts the metabolism of the parasites and bacteria, leading to their death and the resolution of the infection. This mechanism makes it a versatile treatment option for various gastrointestinal infections, including those caused by protozoa, helminths, and anaerobic bacteria.
Nitazoxanide is available in 500mg and 200mg dosages, with the
Nitazoxanide 500mg dose typically prescribed for adults and older children, and the
Nitazoxanide 200mg dose used for younger children. The exact dosage and duration of treatment depend on the specific infection and the patient’s age and weight
